Geeking Science: That Corny DNA

Nine thousand years ago someone on this side of the pond decided that some wild grass looked tasty. Tasty enough to plant in a controlled manner. Again, and again, and again. For generations.
They passed this plant from what is now southwestern Mexico to neighbors north and south of them. Various paths crossed and recrossed during the domestication process. Now DNA is being used to unlock the convoluted history.
Historic DNA isn’t easy to work with. DNA starts breaking down once the living thing that the sequence programmed is no longer living. If you like puzzles, DNA assembly for history might be for you. Using data from 30 sources, scientists got three which could be sequenced after two years work.
Why I am Geeking about this is the DNA being used to trace lineage. Looking at plants gives us insight into land-use and trading. As more and more DNA is added to the historic databases, we can trace diseases (plants and humans), trade across continents, and climate changes.
Bibliography
“Ancient DNA Continues to Rewrite Corn’s 9,000-Year Society-Shaping History. Smithsonian Press Release. 2020 December 14. https://www.si.edu/newsdesk/releases/ancient-dna-continues-rewrite-corns-9000-year-society-shaping-history (last viewed 4/6/2022)
Malsbury, Erin. “How Ancient DNA Unearths Corn’s A-maize-ing History.” Smithsonian Magazine. 2020 December 14. (last viewed 4/6/2022)

Geeking Science: Percussive Maintenance

Photo by Jonny Gios on Unsplash

Ever work with clumpy soil? Know how hard it is to get your shovel out?

Now imagine if the shovel is 100 million miles away on the Mars Lander.

Sometimes, the only fix is a percussive maintenance.

Robitzski, Dan. “NASA Fixes Mars Lander by Telling It to Hit Itself with a Shovel.” The Byte. 2020 March 18. https://futurism.com/the-byte/nasa-mars-lander-hit-itself-shovel (last viewed 4/6/2022)

Geeking Science: 3D Printed Skin

Photo by Amanda Dalbjörn on Unsplash

3D printing promises many changes which will restructure entire industries, none more promising than the medical field. Already 3D printing is making prothesis for children possible in ways never before, including quick adjustments for growth, different prothesis for different activities, and all the colors and pattern to make it “cool”.

Actual medical replacement of body parts with living tissue have moved more slowly. 3D tissue printing, using a patient’s DNA, is a medical holy grail – no rejection! No lifetime of drugs and suppressed immunity! The challenge is developing the software for printing the parts and creating the “ink” from DNA to print the parts.

Printing of organs – like hearts, lungs, livers, and other highly needed transplants – require scaffolding and the uniqueness of each individual “space” for the organs. Each of these is a one-off and means life-or-death for a person. Internal organs will always require highly skill technical assistance in creation and insertion so long as technology is creating the organs outside the body.

Two products, not as specialized as organs but which are constantly required, would revolutionize the Emergency Room if 3d printing tech machines because as easy to hook up and use as an IV line.

Blood and Skin.

Most Americans understand the constant shortage of blood.

Skin is just as needed. For burn and abrasion events. To seal holes from violence and accidents to prevent infection. To heal scars. To replace skin after skin cancer surgery. To fix gingivitis.

Printing skin for burn victims works about as well as the bandages we have right now.

The problem is skin isn’t JUST skin. It has blood vessels. To bond the printed-skin to the body, it needs to be connected to the network of blood and other fluids.

Recently scientists have figured out how to leave a tunnel in the printed-skin which, when attached to a living system, will be converted into blood vessels.

One step closer to every ER having a machine where the techs and nurses just scrape back the damage, dump bio-waste in the machine to use the DNA base, and print the new skin on the body. Burns over half the leg will become an overnight observation to make sure the bond is complete, and the person is sent home. Scraped arms from a fall down the mountain, sealed with the printed-skin  to prevent infection and healed without scars. Dental surgery to cover gingivitis clefts will no longer have to steal skin from other places in the mouth, making two injuries, but instead will be a quick scrap – come back in three days – and fix the gums.

Oh, and once mouth “skin” is mastered – replacement teeth will be possible too. (Did you know that teeth are skin, not bone?) Imagine, no more root canals with fake teeth replacements – but whole and healthy teeth!

Bibliography

Gander, Kashmira. “3D-printed Living Skin With Blood Vessels Created by Scientists.” Newsweek. 2019 November 4. https://www.newsweek.com/3d-printed-living-skin-blood-vessels-scientists-1469507 (last viewed 3/31/2022)

 

Geeking Science: Flipping

I have previously talked about Uranus’ weird tilt and magnetic sphere flips. Earth’s magnetic poles also flip, but much more slowly, about every 200,000 to 300,000 year. Think a quarter of a million years. Nothing to worry about.
Except last flip was 786,000 years ago; we are way overdue.
How would a flip impact us?
First, the field grows weaker right before the flip. Maybe to as little as 10% of normal. Since one of the things the magnetic sphere does is protect the living things on the planet’s surface from solar radiation, an increase of genetic mutation (cancer … especially skin cancer) would increase. Temperature might also rise on the surface, because, yeah, we need more of that.
Second, the magnetic poles wobble around for a while. Magnetic north moves miles in one direction or the other. Anything working on magnetic pole location, like satellites (which give us GPS), will have a rough time. As the wobbles occur all the time, programming has taken care of much of this issue already. Birds don’t seem to have an issue either.
Third, for humans, the flip doesn’t just “stick” the first time. It flips back and forth for a few decades (maybe centuries … the geological record isn’t really clear). That will be a problem. A lot of tech is magnetic base. Self-driving cars and planes are just some of the tech that will be impacted.
A magnetic flip may take down electrical grids. The article I read said “decades” but I think weeks. I consider this just another reason to go solar. Micro-management of some energy with solar houses will keep things humming even if larger grids go down. The combination of large grids and micro-grids gives flexibility for survival.
Bibliography
Dnews / Seeker. “What Happens When Earth’s Magnetic Poles Reverse?” Seeker. 2014 October 21. https://www.youtube.com/watch?v=Ou1BiorYRNU (last viewed 4/1/2022)
Gohd, Chelsea. “The Earth’s Magnetic Poles Are Overdue for a Switch.” Futurism. 2018 January 29. https://futurism.com/earths-magnetic-poles-overdue-switch (last viewed 4/1/2022)

Geeking Science: Poisons

The assassin smiled as she watched the target drink the poison. Any moment now the victim would keel over … any moment.
Or not.
Depends on the poison. Poison isn’t a simple roll d20 for a fail or save. Some poisons require build up over time. Others are skin contact, not ingestion. Some just make you sick, other destroy organs, causing not just a slow death, but an agonizing one.
I recently read an article from Dan Koboldt who likes to put “Science in Sci-Fi, Fact in Fantasy”: “Poisons in SSF“, published April 21, 2016 – he interviewed a toxicology specialist for his posting.
Tropes touched on:
1. All poisons do is kill. (the reproductive toxicity is scary in the non-killing versions of poisons)
2. Poisons work when you eat and drink them.
Find out how to approach and update these common poison tropes and make your fantasy or science-fiction assassin more vicious and unpredictable, read the article and tap the resource links at the end. Again, the link is: http://dankoboldt.com/poisons-in-sff/